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nlrpc inhibitor mcc950  (InvivoGen)


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Bioz Manufacturer Symbol InvivoGen manufactures this product  
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    Structured Review

    InvivoGen nlrpc inhibitor mcc950
    Nlrpc Inhibitor Mcc950, supplied by InvivoGen, used in various techniques. Bioz Stars score: 97/100, based on 304 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nlrpc+inhibitor+mcc950/MCC950/bio_rxiv__64898__2026__02__20__707105-269-17-25
    Average 97 stars, based on 304 article reviews
    nlrpc inhibitor mcc950 - by Bioz Stars, 2026-10
    97/100 stars

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    Activation Assay:

    Article Title: Hijacking of inflammasome responses by the complement system during Pseudomonas aeruginosa – Aspergillus fumigatus sur-infection
    Article Snippet: .. To evaluate inflammasome activation, BMDMs were treated with various inhibitors at the time of A. fumigatus superinfection, NLRPC inhibitor MCC950 (10 μM final concentration) (inhibit-mcc, InvivoGen), caspase-1 and caspase-4 inhibitor VX-765 (40 μM final concentration) (inh-vx765i-1, InvivoGen), caspase-8 inhibitor Z-IETD-FMK (20 μM final concentration) (inhibit-ietd, InvivoGen). .. To evaluate CD11b implication, BMDMs were pretreated with either 20μg/mL of inhibitory monoclonal antibody against CD11b (clone M1/70) (#14-0112-86; eBioscience, Invitrogen) or 20μg/mL of IgG2b control (#15277347, eBioscience, Invitrogen) at 37°C and 5% CO 2, 3 h prior to A. fumigatus infection and maintained during the rest of the infection.

    Concentration Assay:

    Article Title: Hijacking of inflammasome responses by the complement system during Pseudomonas aeruginosa – Aspergillus fumigatus sur-infection
    Article Snippet: .. To evaluate inflammasome activation, BMDMs were treated with various inhibitors at the time of A. fumigatus superinfection, NLRPC inhibitor MCC950 (10 μM final concentration) (inhibit-mcc, InvivoGen), caspase-1 and caspase-4 inhibitor VX-765 (40 μM final concentration) (inh-vx765i-1, InvivoGen), caspase-8 inhibitor Z-IETD-FMK (20 μM final concentration) (inhibit-ietd, InvivoGen). .. To evaluate CD11b implication, BMDMs were pretreated with either 20μg/mL of inhibitory monoclonal antibody against CD11b (clone M1/70) (#14-0112-86; eBioscience, Invitrogen) or 20μg/mL of IgG2b control (#15277347, eBioscience, Invitrogen) at 37°C and 5% CO 2, 3 h prior to A. fumigatus infection and maintained during the rest of the infection.



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    nlrpc inhibitor mcc950  (InvivoGen)
    97
    InvivoGen nlrpc inhibitor mcc950
    Nlrpc Inhibitor Mcc950, supplied by InvivoGen, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/nlrpc+inhibitor+mcc950/MCC950/bio_rxiv__64898__2026__02__20__707105-269-17-25
    Average 97 stars, based on 1 article reviews
    nlrpc inhibitor mcc950 - by Bioz Stars, 2026-10
    97/100 stars
    		  Buy from Supplier

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